phosphate depletion syndrome

Etiology: - severe hypophosphatemia (< 1 mg/dL) Clinical manifestations: 1) hematologic abnormalities a) hemolytic anemia b) impaired leukocyte function c) thrombocytopenia 2) central nervous system dysfunction a) numbness b) paresthesias c) weakness d) confusion e) obtundation f) convulsions g) coma Management: 1) oral phosphate (Neutra-Phos) 2) intravenous phosphate (in an ICU setting) 3) see hypophosphatemia

General

syndrome hypophosphatemia

References

Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998