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phlegmasia cerulea dolens
Clinical manifestations:
- proximal deep vein thrombosis of a limb, with sudden severe pain & swelling, cyanosis & edema,
- massive proximal DVTs involve both deep veins & collateral veins
- increased venous stasis, extravasation of venous fluid into the interstitium, painful swelling & violaceous changes
- arterial compromise (may result from compartment syndrome)
* images [2]
Complications:
- reperfusion injury
- acute renal failure
- compartment syndrome
- circulatory collapse & shock
Management:
- anticoagulation
- fasciotomy for acute compartment syndrome
- catheter-directed thrombolysis
Related
deep vein thrombosis (DVT)
General
phlegmasia
References
- Stedman's Medical Dictionary 26th ed, Williams &
Wilkins, Baltimore, 1995
- Lai HT, Huang SH
Phlegmasia Cerulea Dolens with Compartment Syndrome.
N Engl J Med 2018; 378:658
PMID: 29443665 Free full text
http://www.nejm.org/doi/full/10.1056/NEJMicm1704996