PHD finger protein 23 (PDH-containing protein JUNE-1, PHF23)

Function: - phosphorylated upon DNA damage, probably by ATM or ATR Structure: - belongs to the PHF23 family - contains 1 PHD-type zinc finger Alternative splicing: named isoforms=2 Pathology: - chromosomal translocation t(11;17)(p15;p13) involving PHF23 with NUP98 is found in a patient with acute myeloid leukemia

General

PHD finger protein phosphoprotein

Properties

SIZE: entity length = 403 aa MW = 44 kD MOTIF: Breakpoint {120-121} Ser phosphorylation site {S170} glutamate-rich region {248-261} MOTIF: glutamate residue (SEVERAL) Zn finger PHD-type NAME: Zn finger PHD-type SITE: 339-387 EFFECTOR-BOUND: Zn+2

Database Correlations

UniProt Q9BUL5 Pfam PF00628

References

UniProt :accession Q9BUL5