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phenylacetylglutamine
Physiology:
- byproduct of intestinal bacteri break down of dietary protein [2]
Pathology:
- elevated levels increase risk of heart failure & severity, & risk of myocardial infarction, stroke & death [2]
General
aromatic compound
glutamine (NutreStore, Endari)
Database Correlations
PUBCHEM cid=92258
References
- PubChem: 92258
- Hughes S
Product of Gut Microbiome Implicated in Heart Failure Risk.
Medscape. Dec 22, 2022
https://www.medscape.com/viewarticle/986052
- Romano KA, Nemet I, Saha PP et al
Gut Microbiota-Generated Phenylacetylglutamine and Heart Failure.
Circulation: Heart Failure. 2022. Dec 16.
PMID: 36524472
https://www.ahajournals.org/doi/abs/10.1161/CIRCHEARTFAILURE.122.009972