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polyhomeotic-like protein 1 (hPH1, early development regulatory protein 1, PHC1, EDR1, PH1)
Function:
1) component of the Polycomb group (PcG) multiprotein PRC1 complex
2) component of human polycomb repressive complex 1-like
Structure:
- contains 1 FCS-type zinc finger
- contains 1 SAM domain (sterile alpha motif)
Compartment: nucleus
General
zinc finger protein
Properties
SIZE: MW = 105 kD
entity length = 1004 aa
COMPARTMENT: cell nucleus
MOTIF: glutamine-rich region {425-441}
MOTIF: glutamine residue (SEVERAL)
Zinc finger
NAME: Zinc finger
SITE: 791-825
EFFECTOR-BOUND: Zn+2
sterile alpha motif
NAME: sterile alpha motif
SITE: 940-1004
Database Correlations
OMIM 602978
UniProt P78364
Pfam PF00536
References
UniProt :accession P78364
Component-of
Polycomb group multiprotein PRC1 complex (PcG PRC1 complex, hPRC-H, PcG repressive complex 1)