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pharmaceutical agents associated with gynecomastia

1) androgen antagonists a) cyproterone b) flutamide c) finasteride 2) antibiotics a) ethionamide b) isoniazid c) ketoconazole d) metronidazole 3) gastrointestinal agents a) H1 receptor antagonists, cimetidine > ranitidine b) proton pump inhibitors c) metoclopramide 4) antineoplastic agents a) alkylating agents b) methotrexate c) vinca alkaloids d) imatinib 5) antiarrythmics a) amiodarone b) digitoxin 6) antihypertensive agents a) captopril b) enalopril c) Ca+2 channel blockers, nifedipine > verapamil > diltiazem c) alpha methyldopa d) reserpine e) spironolactone* 7) hormones a) anabolic steroids b) estrogens c) chorionic gonadotropin d) somatotropin 8) mental health agents a) diazepam b) haloperidol c) phenothiazines d) tricyclic antidepressants 9) drugs of abuse a) ethanol b) amphetamines c) heroin d) marijuana e) methadone 10) miscellaneous a) auranofin b) diethylpropion c) domperidone d) etretinate e) phenytoin f) penicillamine g) sulindac h) theophylline * 100% of patients taking > 100 mg/day

General

pharmacology

References

  1. Harrison's Principles of Internal Medicine, 13th ed. Companion Handbook, Isselbacher et al (eds), McGraw-Hill Inc. NY, 1995, pg 830
  2. UpToDate 14.1 http://www.utdol.com