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pharmaceutical agents associated with diarrhea

Drugs commonly causing diarrhea (by drug class [1,3,4] Etiology: 1) antibiotics a) erythromycin b) clindamycin c) cephalosporins d) penicillins, ampicillin 2) laxatives a) phenolphthalein b) magnesium citrate c) senna d) bisacodyl e) lactulose f) castor oil g) milk of magnesia 3) anti-arrhythmic agents a) digoxin b) quinidine c) procainamide 4) anti-hypertensive agents a) hydralazine b) beta blockers c) ACE inhibitors, ARBs 5) diuretics a) furosemide b) thiazides 6) hyperlipidemic agents a) clofibrate b) gemfibrozil c) HMG CoA reductase inhibitors - lovastatin d) probucol 6) hypoglycemic agents a) acarbose b) metformin 7) neuropsychiatric agents a) lithium carbonate b) SSRI - fluoxetine (Prozac) c) alprazolam (Xanax) d) valproic acid e) ethosuximide f) L-dopa 8) others a) colchicine b) magnesium-containing antacids c) methyldopa d) non-steroidal anti-inflammatory drugs (NSAIDs) e) gold f) thyroid medications g) theophylline h) chemotherapeutic agents i) enemas j) prostaglandins: misoprostol k) stimulants l) acetylcholinesterase inhibitors - donepezil (Aricept) m) olsalazine n) proton pump inhibitors o) mesalamine p) carbamazepine * Also see: - drugs associated with diarrhea [A-L] - drugs associated with diarrhea [M-Z] Management: - discontinue potentially offending agent(s)

Related

antibiotic-associated diarrhea (AAD) diarrhea

Specific

drugs associated with diarrhea [A-L] drugs associated with diarrhea [M-Z]

General

drug adverse effect(s) of

References

  1. Harrison's Principles of Internal Medicine, 13th ed. Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 215
  2. Senex: An Electronic Reference for Medicine & Molecular Pathology, 2000
  3. Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 238
  4. Medical Knowledge Self Assessment Program (MKSAP) 15, 18, 19. American College of Physicians, Philadelphia 2009, 2018, 2021.