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prostaglandin E1
Pharmacology:
Indications:
- maintenance of patent ductus arteriosus in neonatal cyanotic congenital heart disease
- coarctation of the aorta
- pulmonary artery stenosis
- pulmonary hypertension [3]
- peripheral vascular disease
- erectile dysfunction [3]
Interactions
molecular events
Related
eicosatrienoate cyclooxygenase cascade
prostaglandin-E1 [PGE1] receptor
Specific
alprostadil (Muse, Caverject, Edex, Prostin VR pediatric, Topiglan, Befar)
misoprostol (Cytotec)
General
8,11,14-eicosatrienoate (dihomo gamma-linolenic acid)
prostaglandin E
Properties
SIZE: MW = 306.5 G/MOL
COMPARTMENT: membrane
Database Correlations
PUBCHEM correlations
References
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996 pg
- Merck Index, I2th ed, Merck & Co, Rahway NJ, 1996 # 8062
- Deprecated Reference