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perioperative glucocorticoids

Management: - continue glucocorticoids: - increase if stress dose indicated - equivalent of >= 10-20 mg prednisone per day for at least 3 weeks in the past 6-12 months [1] - perioperative adrenal insufficiency - if high risk (major) surgery - hydrocortisone 50-100 mg IV before surgery, then 25-50 mg IV every 8 hours for 24-48 hours - if low risk surgery: - usual dose of glucocorticoid on day of surgery

Interactions

drug adverse effects of glucocorticoids monitor with drug (more general terms)

General

glucocorticoid

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 14, 15, 16, 17, 18, 19. American College of Physicians, Philadelphia 2006, 2009, 2012, 2015, 2018, 2022.
  2. Woodcock T, Barker P, Daniel S et al Guidelines for the management of glucocorticoids during the peri-operative period for patients with adrenal insufficiency: Guidelines from the Association of Anaesthetists, the Royal College of Physicians and the Society for Endocrinology UK Anaesthesia. 2020 May;75(5):654-663 PMID: 32017012