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pentagastrin (Peptavlon)
Indications:
- pentagastrin-stimulated calcitonin test
Dosage:
- injection 5 ug/kg ideal body weight
Adverse effects:
- panic attack due to activation of cholecystokinin-B receptor
Mechanism of action:
- synthetic polypeptide with gastrin-like effect
- stimulates the secretion of gastric acid, pepsin, & intrinsic factor
- binds to the cholecystokinin-B receptor, widely expressed in brain, in turn activating phospholipase C
General
polypeptide
endocrine agent
Database Correlations
PUBCHEM cid=9853654
References
- Wikipedia: Pentagastrin
https://en.wikipedia.org/wiki/Pentagastrin