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peflin (PEF protein with a long N-terminal hydrophobic domain, penta-EF hand domain-containing protein 1, PEF1, ABP32, UNQ1845/PRO3573)
Function:
1) heterodimer with PDCD6/ALG2
2) dissociates from PDCD6/ALG2 in presence of Ca+2
Compartment:
- cytoplasm
- membrane-associated in the presence of Ca+2
General
Ca+2 binding protein
Properties
SIZE: MW = 30 kD
entity length = 284 aa
MOTIF: consensus repeat {21-29}
[AP]-P-G-G-P-Y-G-G-P-P. {21-109}
MOTIF: consensus repeat {31-39}
consensus repeat {41-49}
consensus repeat {50-58}
consensus repeat {59-67}
consensus repeat {76-84}
consensus repeat {85-92}
consensus repeat {93-100}
consensus repeat {101-109}
EF hand
SITE: 114-149
EF hand
SITE: 155-183
EF hand
SITE: 181-216
binding site
SITE: 204-284
FOR-BINDING-OF: programmed cell death protein 6
MOTIF: EF hand
SITE: 217-253
EF hand
SITE: 254-283
Database Correlations
UniProt Q9UBV8
Pfam PF00036
References
UniProt :accession Q9UBV8