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Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infection (PANDAS)
Controversial syndrome.
PANDAS is the association of:
- obsessive-compulsive disorder (OCD)
- Tourette syndrome, or
- tic disorders
with streptococcal infection.
The association is controversial.
Clinical manifestations:
- clinical symptoms of OCD observed within weeks of pharyngitis [2]
Related
Ailurinae (pandas)
General
pediatric acute-onset neuropsychiatric syndrome (PANS)
References
- Journal Watch 25(16):129, 2005
Mell LK, Davis RL, Owens D.
Association between streptococcal infection and obsessive-
compulsive disorder, Tourette's syndrome, and tic disorder.
Pediatrics. 2005 Jul;116(1):56-60.
PMID: 15995031
- Orlovska S, Vestergaard CH, Bech BH et al.
Association of streptococcal throat infection with mental
disorders: Testing key aspects of the PANDAS hypothesis in
a nationwide study.
JAMA Psychiatry 2017 May 24
PMID: 28538981