phosphodiesterase 1 (PDE1, calcium/calmodulin dependent phosphodiesterase, cyclic nucleotide phosphodiesterase [CNP] type 1)

Along with cyclic nucleotide phosphodiesterase (CNP) type 2, major enzyme of CNS myelin.

Specific

Ca+2/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; Cam-PDE 1A; 61 kD Cam-PDE; hCam-1 (PDE1A) Ca+2/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; Cam-PDE 1B; 63 kD Cam-PDE (PDE1B, PDE1B1, PDES1B) Ca+2/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Cam-PDE 1C; hCam-3 (PDE1C) ectonucleotide pyrophosphatase/phosphodiesterase family member 2; E-NPP 2; autotaxin; extracellular lysophospholipase D; lysoPLD; phosphodiesterase 1 alpha (ENPP2, ATX, PDNP2)

Properties

MOTIF: active site domain MOTIF: histidine residue (2)

References

Agrawal et al J Biol Chem 1990 Jul 15;265(20):11849-53