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parkin gene

Pathology: - mutations associated with autosomal recessive juvenile Parkinson disease Notes: - SNPs in gene associated with exceptional longevity in humans

Related

E3 ubiquitin-protein ligase parkin; EC=6.3.2.-; parkinson juvenile disease protein 2; parkinson disease protein 2 (PARK2 PRKN)

General

unclassified gene

Properties

TEMPLATE-FOR: messenger RNA TEMPLATE-FOR: E3 ubiquitin-protein ligase parkin LOCUS: human chromosome-6 Q25.2-27 MOTIF: transcription factor binding site transcriptional start site exon intron transcriptional termination site

Database Correlations

OMIM correlations MORBIDMAP 602544

References

  1. Sebastiani P et al Genetic signatures of exceptional longevity in humans. PLoS One. 2012;7(1):e29848. Epub 2012 Jan 18. PMID: 22279548