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paricalcitol (Zemplar)

Indications: - treatment of hyperparathyroidism of chronic kidney disease - treatment of diabetic nephropathy [2] in combination with ACE inhibitor or ARB Dosage: 1-2 ug PO QD Capsule Mechanism of action: - activates vitamin D receptor - reduces albuminuria in patients with diabetic nephropathy [2]

Related

hyperparathyroidism

General

endocrine agent

Database Correlations

PUBCHEM correlations

References

  1. Prescriber's Letter 13(2): 2006 Detail-Document#: 220215 (subscription needed) http://www.prescribersletter.com
  2. de Zeeuw D et al. Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): A randomised controlled trial. Lancet 2010 Nov 6; 376:1543 PMID: 21055801