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parathyroid hormone related peptide in plasma
Indications:
1) useful for distinguishing primary hyperparathyroidism from hypercalcemia due to malignancy
2) useful as a marker in the management of patients with tumor-associated hypercalcemia
Specimen:
1) plasma (heparin)
2) collect in tubes that contain protease inhibitor (aprotinin & leupeptin)
3) chill specimens immediately in icewater
4) plasma should be separated in a refrigerated centrifuge, then frozen immediately at -20 degrees C in plastic vials
Reference values:
- < 1.5 pmol/L (adult)
Increases:
-> humoral hypercalcemia of malignancy
a) lymphomas
b) squamous cell carcinoma of the lung
c) breast cancer
Related
hypercalcemia of malignancy
parathyroid hormone [PTH]-related protein
General
special chemistry test
References
- Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed.,
W.B. Saunders, 1995
- Parathyroid Hormone Related Peptide
Laboratory Test Directory ARUP: 93014