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papilloma virus 16 Ag in tissue

Indications: - head & neck cancer Clinical significance: - cure rate for locally-advanced head & neck cancer associated with HPV is much higher that without [1] - at least some confusion about p16ink4a & papilloma virus 16 Ag in tissue since it seems HPV may induce expression of p16ink4a in squamous cell head & neck cancers [2]

General

papilloma virus antigen in tissue

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015
  2. Stephen JK, Divine G, Chen KM et al Significance of p16 in Site-specific HPV Positive and HPV Negative Head and Neck Squamous Cell Carcinoma. Cancer Clin Oncol. 2013;2(1):51-61. PMID: 23935769 Free PMC Article