papillary renal cell carcinoma

Also see renal cell carcinoma Epidemiology: 15-20% of renal cell carcinomas Pathology: - immunocytochemistry: - cytokeratin AE1/AE3: positive - vimentin: positive Genetics: - multiple translocations involving TFE3 on chromosome Xp11 a) t(X;17)(p11;q25) involving ASPSCR1 & TFE3 b) t(X;1)(p11.2;q21.2) involving PRCC & TFE3 c) t(X;1)(p11.2;p34) involving SFPQ with TFE3 Clinical manifestations: - generally presents with hematuria

Specific

papillary renal cell carcinoma 2; hereditary papillary renal carcinoma (HPRC, RCCP2) papillary renal cell carcinoma [MET mutation] papillary renal cell carcinoma [RCCP1] papillary renal cell carcinoma [RCCP3]

General

papillary adenocarcinoma renal cell carcinoma (hypernephroma, Grawitz tumor)

References

Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998