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palmare xanthoma
Etiology:
- familial dysbetalipoproteinemia (familial hyperlipoproteinemia type 3) (pathognomonic)
Epidemiology:
- rare
Clinical manifestations:
- painful
- affecting every day life
- difficulty opening bottles or shaking hands
Laboratory:
- lipid panel
- increased serum total cholesterol
- increased LDL cholesterol
Management: LDL apheresis [2]
General
xanthoma
References
- NEJM Knowledge+ Endocrinology
- Koehler VF, Parhofer KG.
Images in Clinical Medicine. Xanthoma Striatum Palmare.
N Engl J Med 2018; 378:e26. May 10, 2018
PMID: 29742369
https://www.nejm.org/doi/full/10.1056/NEJMicm1713658