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odynophagia (swallowing pain)

Pain on swallowing. Etiology: 1) mucosal inflammation: sharp burning pain a) reflux esophagitis b) esophageal infection (generally opportunistic) - Candida - Herpes virus - cytomegalovirus - bacterial esophagitis c) pill esophagitis 2) muscular spasm: squeezing, cramping pain 3) distension of the esophagus 4) tonsillitis 5) laryngitis 6) epiglottitis 7) upper respiratory tractions 8) xerostomia 9) Zenkers diverticulum 10) adenoiditis 11) immune disorders 12) esophageal cancer 13) myasthenia gravis 14) scleroderma 15) Behcet's syndrome [7] 16) hyoid bone syndrome 17) foreign body ingestion 18) radiation injury 19) caustic chemical ingestion 20) Crohn's disease (rare) 21) pancreatic pseudocyst (rare) 22) sexually-transmitted disease - secondary syphilis, gonorrhea, Herpes simplex [8] Clinical manifestations: - association with dysphagia - may occur on a background of heartburn Special laboratory: - swallowing study - upper endoscopy Radiology: - anteroposterior & lateral neck X-ray - chest X-ray Management: - depends upon specific etiology

Related

chest pain dysphagia (swallowing disorder) pyrosis (heartburn)

General

pain [odyn-]

References

  1. Stedman's Medical Dictionary 26th ed, Williams & Wilkins, Baltimore, 1995
  2. Guide to Physical Examination & History Taking, 6th edition, Bates B, JB Lippincott, Philadelphia, 1995, pg 42
  3. Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 336
  4. Common causes of Odynophagia http://www.wrongdiagnosis.com/symptoms/odynophagia_similar_to_that_in_achalasia_cardia/common.htm
  5. Strom EA Odynophagia http://www.med.ucla.edu/modules/wfsection/article.php?articleid=280
  6. Medical Knowledge Self Assessment Program (MKSAP) 15, American College of Physicians, Philadelphia 2009
  7. Unizony SH, Kim ND, Hoang MP. Case Records of the Mass General Hospital. Case 7-2015: A 25-year-old man with oral ulcers, rash, and odynophagia. N Engl J Med. 2015 Feb 26;372(9):864-72 PMID: 25714165 http://www.nejm.org/doi/full/10.1056/NEJMcpc1413303
  8. Barbee LA et al A History Lesson. N Engl J Med 2015; 372:1360-1364. April 2, 2015 PMID: 25830427 http://www.nejm.org/doi/full/10.1056/NEJMcps1308900