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PAH gene mutation; phenylalanine hydroxylase gene mutation; phenylketonuria genotyping

Indications: - phenylketonuria Specimen: 1) whole blood (ACD or EDTA) 2) store whole blood at 4 degrees C Clinical significance: - severity of hyperphenylalaninemia & phenylketonuria correlates with extent of mutation

Related

phenylalanine-4-hydroxylase; phenylalanine-4-monooxygenase (PAH) phenylketonuria (PKU)

General

gene mutation testing; gene mutation analysis

References

  1. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
  2. Loinc