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ovarian cancer genotyping

Indications: - ovarian cancer Specimen: 1) tumor tissue 2) paraffin-embedded tissue 3) store fresh tissue at 4 degrees C for 24 hours 4) store tissue at -20 degrees C or below Genetics: - associated genetic aberrations: - BRCA1/BRACA2 mutations (all women) - mismatch repair mutations/HNPCC gene mutations (all women) - ras proto-oncogene - p53 gene

Related

ovarian cancer p53 gene ras proto-oncogene

General

genotyping (allele testing)

References

  1. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
  2. Medical Knowledge Self Assessment Program (MKSAP) 18, American College of Physicians, Philadelphia 2018
  3. ARUP Consult: Ovarian Cancer The Physician's Guide to Laboratory Test Selection & Interpretation https://www.arupconsult.com/content/ovarian-cancer - ARUP Consult: Hereditary Breast and Ovarian Cancer https://arupconsult.com/ati/hereditary-breast-and-ovarian-cancer