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Ornish Intensive Lifestyle changes
Clinical trials:
- Ornish Intensive Lifestyle changes improved cognition in patients with mild cognitive impairment or early dementia
- four components:
- a whole-food, minimally processed, plant-based diet of predominantly fruits, vegetables, whole grains, legumes, & selected supplements
- moderate aerobic exercise (walking) & strength training for >= 30 minutes/day
- stress management including meditation, stretching, breathing, & imagery for 1 hour a day
- online support groups for participants & spouses or study partners for 1-hour sessions three times a week
Notes:
- how does the Ornish intervention compare with Alzheimer monoclonal antibodies lecanemab, donanemab, aducanumab & others?
General
life-style
References
- George J
Alzheimer's Slowed by Intensive Lifestyle Changes
Small trial led by Dean Ornish, MD, shows cognitive improvement.
MedPage Today June 11, 2024
https://www.medpagetoday.com/neurology/alzheimersdisease/110596
- Ornish D, Madison C, Kivipelto M et al.
Effects of intensive lifestyle changes on the progression of mild cognitive
impairment or early dementia due to Alzheimer's disease: a randomized, controlled
clinical trial.
Alzheimers Res Ther. 2024. Jun 7;16(1):122.
PMID: 38849944 PMCID: PMC11157928 Free PMC article. Clinical Trial