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orbital cellulitis

Etiology: - associated conditions - sinusitis - dental infection Pathology: - inflammation of structures of the orbit, including extraocular muscles & orbital fat - bacterial infection that involves the soft tissue posterior the orbital septum Clinical manifestations: 1) swelling & erythema of the eyelids & conjunctiva (chemosis) 2) unilateral proptosis may be present 3) ophthalmoplegia: restriction of eye movements 4) afferent pupillary defect 5) eye pain - pain with eye movement 6) visual impairment when severe 7) fever Laboratory: - complete blood count (CBC) may show leukocytosis - Gram stain - culture both aerobic & anaerobic media - collect purulent material from the nose with a cotton or calcium alginate swab - fine needle aspiration of the orbit is contraindicated [3] Radiology: - CT scan or MRI of the sinuses & orbit Complications: - cavernous sinus thrombosis - hearing loss - septicemia - meningitis - optic nerve damage & loss of vision Differential diagnosis: - optic neuritis - loss of color vision affected more severely than visual acuity - no fever or chemosis - acute angle-closure glaucoma Management: - admit to hospital - fever, leukocytosis - failure of oral antibiotics - immunosuppression [5] - intravenous antibiotics targeting likely organisms a) Streptococcus b) Staphylococcus - immediate referral to or consultation with ophthalmologist

General

orbital inflammation eye infection (ocular infection) cellulitis

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 11, 15, 17, 18. American College of Physicians, Philadelphia 1998, 2009, 2015, 2018.
  2. PubMed Health: Orbital Cellulitis http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002007/
  3. Harrington JN eMedicine (Medscape): Orbital Cellulitis http://emedicine.medscape.com/article/1217858-overview
  4. Gelston CD. Common eye emergencies. Am Fam Physician. 2013 Oct 15;88(8):515-9. Review. PMID: 24364572 Free Article
  5. NEJM Knowledge+ Ophthalmology