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Orasure Rapid HIV-1 Antibody Test (on-the-spot HIV test)
Indications:
- HIV1 infection
Clinical significance:
- HIV screening tests
- results need to be confirmed by more specific test (i.e. HIV1 Western Blot)
- 1 test uses fingerstick blood sample [1]
- the other uses a treat cotton swab along the gums to pick up epithelial cells lining the mouth [2]
- either test takes about 20 minutes
- FDA approved for use in hospitals & clinics.
Procedure:
1) fingerstick
- a lancet draws a blood droplet which is transferred to a plastics specimen loop
- the sample is mixed with a developing solution
- a test reading device is dipped into a vial & incubated for 20 minutes
- the test uses a strip of HIV proteins to detect antibody
- a single pink line at the control area means the test is negative; two pink lines is a positive test (i.e. indication of HIV infection)
2) oral cotton swab test
- the swab is placed into a stick-like device
- infection is determined by the presence of reddish-purple lines that appear in a window
Notes:
- accuracy of test is 99.6% (blood test); 99% (cotton swab test)
- anyone with simple training can administer the test
- cost $12 (2003)
- Abbott & Orasure Technologies
Related
Oraquick Rapid HIV-1 Antibody Test (on-the-spot HIV test)
General
rapid HIV test (point of care HIV test)
References
- Prescriber's Letter 10(3):15 2003
- http://www.orasure.com
Associated Press (03/27/04)