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nuclear transfer (therapeutic cloning)
Procedure:
- the nucleus from a donated egg is replaced by the nucleus from a patient's cell
- the egg grows into a blastocyst
- embryonic stem cells are extracted & cultured
- the cultured embryonic stem cells may be introduced into the patient for embryonic stem cell therapy.
Related
embryonic stem (ES) cell
References
- Journal Watch 25(13):101, 2005
Hwang WS, Roh SI, Lee BC, Kang SK, Kwon DK, Kim S, Kim SJ,
Park SW, Kwon HS, Lee CK, Lee JB, Kim JM, Ahn C, Paek SH,
Chang SS, Koo JJ, Yoon HS, Hwang JH, Hwang YY, Park YS, Oh SK,
Kim HS, Park JH, Moon SY, Schatten G.
Patient-specific embryonic stem cells derived from human SCNT
blastocysts.
Science. 2005 Jun 17;308(5729):1777-83. Epub 2005 May 19.
PMID: 15905366
http://www.sciencemag.org/cg/rapidpdf/1112286v1