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nuclear receptor corepressor (N-COR)

Function: - interacts with unliganded nuclear receptors, including RXR, RAR, T3R, & PPAR-alpha to keep them in a repressed state

Specific

nuclear receptor corepressor 1; N-CoR1; N-CoR (NCOR1 KIAA1047) nuclear receptor corepressor 2; N-CoR2; silencing mediator of retinoic acid & thyroid hormone receptor; SMRT; thyroid-, retinoic-acid-receptor-associated corepressor; T3 receptor-associating factor; TRAC; CTG repeat protein 26; SMAP270 (NCOR2, CTG26)

General

transcriptional silencer (transcriptional repressor)

Properties

COMPARTMENT: cell nucleus

References

  1. Corton JC, Anderson SP, Stauber A. Central role of peroxisome proliferator-activated receptors in the actions of peroxisome proliferators. Annu Rev Pharmacol Toxicol. 2000;40:491-518. Review. PMID: 10836145