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nuclear pore complex (NPC)
nuclear pore components are collectively referred to as nucleoporins
Function:
- allows diffusion of ions, small molecules, & proteins < 40-60 kD through the nuclear membrane
Structure: 8-fold symmetry
Related
nucleoporin SEH1 (SEC13-like protein)
General
macromolecular complex
Properties
SIZE: MW = 120000 kD
WIDTH = 10-20 NM
COMPARTMENT: nuclear membrane
References
- Molecular Biology of the Cell (2nd ed) Darnell J;
Lodish H & Baltimore D (eds), Scientific American Books,
WH Freeman, NY 1990, pg 274
- Nigg EA, Baeuerle PA, Luhrmann R.
Nuclear import-export: in search of signals and mechanisms.
Cell. 1991 Jul 12;66(1):15-22. Review. No abstract available.
PMID: 1712670
Components
nucleoporin (nuclear pore complex protein)