Search
nodular basal cell carcinoma
Epidemiology:
- 40-60% of basal cell carcinomas (most common type)
Clinical manifestations:
1) pearly or translucent nodule or papule with arborizing telangiectasias
- generally occurs as solitary red nodule with telangiectasias, arising on skin with dermatoheliosis
2) translucent, flesh colored papule often with telangiectasias overlying the translucent border
3) a waxy, pearly appearance may be noted when the overlying skin is stretched
4) may have central depression or ulceration with a rolled waxy border
- ulceration with crusting occurs centrally as the lesion enlarges
5) bleeding when washing of shaving may be noted
Special laboratory:
- skin biopsy
Differential diagnosis:
1) sebaceous hyperplasia
2) fibrous papule of the nose
3) dermal melanocytic nevus
4) amelanocytic melanoma
5) milium
6) chondrodermatitis nodularis*
* only lesion in the differential that also ulcerates
Management:
- see basal cell carcinoma
Database Correlations
OMIM 605462
References
- Color Atlas and Synopsis of Clinical Dermatology, Common
and Serious Diseases, 3rd ed, Fitzpatrick et al, McGraw Hill, NY,
1997, pg 214-17
- Medical Knowledge Self Assessment Program (MKSAP) 11, 16.
American College of Physicians, Philadelphia 1998, 2012