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neuromedin-U; contains: neuromedin-U-25; NmU-25 (NMU)
Function:
- stimulates muscle contractions of specific regions of the gastrointestinal tract
- in humans, NmU stimulates contractions of the ileum & urinary bladder
Structure: belongs to the NmU family
Compartment: secreted
Expression:
- expressed throughout the enteric nervous system
- highest levels being found in the jejunum
General
neuropeptide
Properties
SIZE: entity length = 174 aa
MW = 20 kD
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-34}
Database Correlations
OMIM 605103
UniProt P48645
Pfam PF02070
Entrez Gene 10874
Kegg hsa:10874
References
UniProt :accession P48645