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N-myc-interactor (Nmi, N-myc & STAT interactor, NMI)
Function:
1) role in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors
2) enhances cytokine-mediated STAT transcription
3) enhances CBP/p300 coactivator protein recruitment to STAT1 & STAT5
4) interacts with N-myc & C-myc, as well as with other transcription factors with a Zip, HLH or a HLH-Zip motif
5) interacts with all STAT proteins except STAT2
6) induced by interleukin-2 & interferon gamma
Compartment: cytoplasm
Expression:
- expressed in all adult & fetal tissues except brain & skin
- more abundant in fetal tissues, especially liver
General
other protein
Properties
SIZE: MW = 35 kD
entity length = 307 aa
COMPARTMENT: cytoplasm
Database Correlations
OMIM 603525
UniProt Q13287
References
UniProt :accession Q13287