nitroblue tetrazolium test

Indications: - chronic granulomatous disease Clinical significance: - normally, NADPH oxidase of neutrophils oxidizes nitroblue tetrazolium to form a blue color - in patients with chronic granulomatous disease, neutrophils are defective in NADPH oxidase and do not oxidize nitroblue tetrazolium, thus do not form a blue color Decreases: - chronic granulomatous disease

References

- Medline Plus http://www.nlm.nih.gov/medlineplus/ency/article/003355.htm