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nigericin
Antiport, electroneutral. Nigericin is a K+/H+ ionophore that alters K+ homeostasis & activates a plasma membrane ATPase (2).
Interactions
drug interactions
General
alcohol
carboxylate
ionophore
other antibiotic
Properties
COMPARTMENT: membrane
ION-PERMEABILITY: H+
K+
Database Correlations
PUBCHEM correlations
References
- Textbook of Biochemistry with Clinical Correlations,
3rd ed., TM Devlin (ed), Wiley-Liss, NY 1992 pg 232
- Kuida K, Lippke JA, Ku G, Harding MW, Livingston DJ, Su MS,
Flavell RA.
Altered cytokine export and apoptosis in mice deficient in
interleukin-1 beta converting enzyme.
Science. 1995 Mar 31;267(5206):2000-3.
PMID: 7535475
Substructures
tetrahydropyran; oxacyclohexane
tetrahydrofuran