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nicotinic receptor alpha
Function:
- subunit of nicotinic receptor
- subunit of nicotinic receptor (muscle), a pentamer of two alpha chains, & one each of the beta, delta, & gamma (in immature muscle) or epsilon (in mature muscle) chains
- one of 2 subunits in pentameric neuronal nicotinic receptor (alpha, beta)
Specific
neuronal acetylcholine receptor subunit alpha-6 (CHRNA6)
nicotinic receptor alpha-10; neuronal acetylcholine receptor subunit alpha-10; nicotinic acetylcholine receptor subunit alpha 10; NACHR alpha 10 (CHRNA10, NACHRA10)
nicotinic receptor alpha-1; acetylcholine receptor subunit alpha-1 (CHRNA1, ACHRA, CHNRA)
nicotinic receptor alpha-2; neuronal acetylcholine receptor subunit alpha-2 (CHRNA2)
nicotinic receptor alpha-3; neuronal acetylcholine receptor subunit alpha-3 (CHRNA3, NACHRA3)
nicotinic receptor alpha-4; neuronal acetylcholine receptor subunit alpha-4 (CHRNA4, NACRA4)
nicotinic receptor alpha-5; neuronal acetylcholine receptor subunit alpha-5 (CHRNA5, NACHRA5)
nicotinic receptor alpha-7, neuronal acetylcholine receptor subunit alpha-7 (CHRNA7, NACHRA7, alpha 7 nAChR)
nicotinic receptor alpha-9; neuronal acetylcholine receptor subunit alpha-9; nicotinic acetylcholine receptor subunit alpha 9; NACHR alpha 9 (CHRNA9, NACHRA9)
General
glycoprotein
ionotropic receptor subunit
transmembrane 4e protein
Properties
COMPARTMENT: plasma membrane
MOTIF: exoplasmic domain {N-TERMINAL}
glycosylation site
transmembrane domain {TM1}
transmembrane domain {TM2}
transmembrane domain {TM3}
transmembrane domain {TM4}
exoplasmic domain {C-TERMINAL}
cytoplasmic domain {C-TERMINAL}
MOTIF: hydrophobic region
Database Correlations
OMIM 100690
Entrez Gene 1134
References
- OMIM :accession 100690
- Entrez Gene :accession 1134
Component-of
nicotinic receptor (nicotinic acetylcholine receptor, nAChR)