niclosamide (Niclocide, Clonitralid, Bayluscide)

Tradename: Niclocide. Indications: - treatment of intestinal tapeworms a) beef tapeworm b) fish tapeworm c) dwarf tapeworm Dosage: 1) beef tapeworm & fish tapeworm a) adults: 2 g (4 tablets) as single dose b) children: - 11-34 kg: 1 g as single dose - > 34 kg: 1.5 g as single dose 2) dwarf tapeworm a) adults: 2 g in a single daily dose for 7 days b) children: - 11-34 kg: 1 g chewed thoroughly in a single dose on day 1, then 500 mg QD for 6 days - > 34 kg: 1.5 g as single dose on day 1, then 1 g QD for 6 days Tablets: (chewable) 500 mg. Adverse effects: 1) not common (1-10%) - drowsiness, dizziness, headache, nausea/vomiting, loss of appetite, diarrhea 2) uncommon (< 1%) - palpitations, edema in the arm, rash, pruritus ani, alopecia, oral irritation, fever, taste disturbance*, constipation, rectal bleeding, weakness, backache, diaphoresis * bad taste in mouth

References

Kaiser Permanente Northern California Regional Drug Formulary, 1998