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neuropathic ulcer

Etiology: - repetitive skin trauma - diabetic neuropathy Pathology: - occurs due to unrecognized trauma to insensate feet - ulcers are generally much deeper & wider than their surface appearance suggests - commonly surrounded by a thick, macerated rim of hyperkeratosis [1] Clinical manifestations: - generally asymptomatic (painless), except for associated diabetic paresthesias - occur primarily on plantar aspect of the foot, especially in the region of the metatarsal heads - thickened surrounding hyperkeratosis is common * image [3] Complications: - osteomylelitis - amputation Special laboratory: - ankle-brachial index Radiology: - X-ray of foot - computed tomography - bone scan Management: - rule out or rule in osteomyelitis - assess vascular supply - debridement of necrotic tissue - offload pressure - appropriate footwear vs total-contact casting - prevention & early identification in patients with diabetes mellitus - self daily examination of feet - professional foot examination every clinic visit

Related

arterial ulcer pressure ulcer (decubitus ulcer, bedsore) venous stasis ulcer

Specific

diabetic foot ulcer; diabetic foot lesion; diabetic lower extremity lesion

General

cutaneous ulcer chronic skin disease (chronic dermatologic disorder, chronic dermatopathy, chronic dermatosis) chronic neurologic disease

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 15, 16, 17, 18. American College of Physicians, Philadelphia 2009, 2012, 2015, 2018.
  2. Boulton AJ. What you can't feel can hurt you. J Vasc Surg. 2010 Sep;52(3 Suppl):28S-30S PMID: 20804930
  3. London Health Sciences Centre (image) Diabetic/Neuropathic Ulcer http://www.lhsc.on.ca/Health_Professionals/Wound_Care/diabetic.htm