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nandrolone (Deca-Durabolin [decanoate], Durabolin [phenylpropionate])

Nandrolone decanoate. Tradename: Deca-Durabolin. Indication: management of anemia of renal insufficiency Dosage: 1) IM dosing only 2) men: 100-200 mg IM weekly 3) women: 50-100 mg IM weekly Nandrolone phenylpropionate. Tradename: Durabolin. 50-100 mg IM weekly Adverse effects: 1) nausea/vomiting 2) diarrhea 3) virilization 4) acne 5) gynecomastia 6) testicular atrophy 7) changes in libido 8) females: a) hirsuitism b) deepening of voice c) clitoral enlargement 9) chronic effects (long term use) a) peliosis hepatis b) liver cell tumors c) increased risk of atherosclerosis Drug interactions: 1) increased anticoagulant effect of warfarin 2) increased hypoglycemic effect of sulfonylureas Mechanism of action: anabolic steroid

Interactions

drug adverse effects of androgens

Related

peliosis hepatis

General

androgen or anabolic steroid

Properties

MISC-INFO: elimination route LIVER pregnancy-category X safety in lactation -

Database Correlations

PUBCHEM correlations

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998