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N-acetylaspartylglutamate (NAAG)
Function:
- specific endogenous agonist of mGluR3
- hydrolyzed by glutamate carboxypeptidase-2
Pathology:
- may play a protective role in schizophrenia
Laboratory:
- N-acetylaspartylglutamate in CSF
Related
NMDA receptor
General
amine
carboxylate
Database Correlations
PUBCHEM correlations
References
- Ghose S et al.
Differential expression of metabotropic glutamate receptors
2 and 3 in schizophrenia: A mechanism for antipsychotic drug
action?
Am J Psychiatry 2009 Jun 1; [e-pub ahead of print].
PMID: 19487395
http://dx.doi.org/10.1176/appi.ajp.2009.08091445