Contents

Search


myxopapillary ependymoma

Epidemiology: - tend to be located in conus/cauda equina/filum terminale region - most common intramedullary neoplasm in this region - can occur in cervical-thoracic cord, lateral ventricle, brain parenchyma - age range 6 to 82 years Microscopic Pathology: - cuboidal to elongated uniform cells - radial arrangement in papillary manner around vascularized stromal cores - mucoid matrix - microcysts - mitoses low to absenthistopathology Electron microscopy: - complex interdigitations - abundant basement membrane structures - few cilia - aggregation of microtubules within rough ER complexes Immunohistochemistry: GFAP + S 100 + vimentin + cytokeratin - Clinical manifestations: - back pain, often long duration Radiology: - MRI: circumscribed enhancing lesion Differential diagnosis: - chordoma - myxoid chondrosarcoma - paraganglioglioma - mesothelioma - papillary adenocarcinoma - pilocytic/pilomyxoid astrocytoma - chordoid glioma

General

ependymal neoplasm

References

  1. WHO Classification Tumours of the Nervous System. Kleihues & Cavenee eds. IARC Press 2000

Images

images related to myxopapillary ependymoma