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myosin

large family of motor proteins found in eukaryotic tissues Function: - actin-based motility - component of actomyosin - muscle contraction Structure: - muscle myosin is a hexameric protein that consists of a) 2 myosin heavy chain subunits b) 2 myosin essential light chain subunits c) 2 myosin regulatory light chain subunits

Interactions

molecular events

Related

unconventional myosin

General

contractile protein microfilament protein multisubunit protein phosphoprotein

Properties

COMPARTMENT: cytoplasm SUBUNITS: myosin heavy chain CONFIGURATION: dimer MOTIF: coiled coil P-loop FOR-BINDING-OF: adenosine triphosphate src homology 3 [SH3] domain myosin essential light chain myosin regulatory light chain MOTIF: Ser phosphorylation site EF hand

References

  1. Pawson T Protein modules and signalling networks Nature 373:573 1995 PMID: 7531822
  2. Wikipedia: myosin http://en.wikipedia.org/wiki/Myosin

Component-of

actomyosin

Components

myosin essential (alkali) light chain myosin heavy chain myosin regulatory light chain (MRLC)