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Mycoplasma genitalium

Epidemiology: - emerging STD - 21% of young women in on study [2] - infection (vs colonization) persists for > 12 months - incidence higher in black women [2] Clinical manifestations: - urethritis & cervicitis like chlamydia Laboratory: - Mycoplasma genitalium DNA - nucleic acid amplification tests are the only reliable method of diagnosis - may not be widely available Management: 1) continue to follow the CDC recommendations for urethritis but .. doxycycline is not reliable, azithromycin once ? -> azithromycin for 5 days (Z-Pak) 500 mg day 1, then 250 mg QD 2) oxifloxacin (Avelox) 400 mg daily for 10 days is sometimes effective

General

Mycoplasma

Properties

KINGDOM: monera DIVISION: SCHIZOMYCETES

References

  1. Prescriber's Letter 14(8): 2007 Mycoplasma genitalium: An Emerging Sexually Transmitted Disease Detail-Document#: 230802 (subscription needed) http://www.prescribersletter.com
  2. Sena AC, Lee JY, Schwebke J et al. A silent epidemic: The prevalence, incidence and persistence of Mycoplasma genitalium among young, asymptomatic high-risk women in the United States. Clin Infect Dis 2018 Jun 18; 67:73-79. PMID: 29342269 https://academic.oup.com/cid/article-abstract/67/1/73/4802235
  3. Loinc
  4. Wikipedia: Mycoplasma genitalium https://en.wikipedia.org/wiki/Mycoplasma_genitalium