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Mycobacterium tuberculosis (MTB)
Pathology:
- Mycobacterial isocitrate lyase protects MTB against interferon-mediated macrophage elimination
Laboratory:
- aerobic, non-motile, acid alcohol fast, slightly curved or straight bacteria
- cell walls contain mycolic acids as do other Mycobacterium
- M tuberculosis is slow growing in culture with 4-6 weeks required for growth on Lowenstein-Jensen media
- M tuberculosis DNA testing is considerably faster
- see Mycobacterium, tuberculosis & ARUP consult [3]
Related
Mycobacterium & acid-fast bacterium (AFB) culture
Mycobacterium tuberculosis DNA
tuberculosis
tuberculous arthritis
Tuberculous Esophagitis
tuberculous meningitis
tuberculous peritonitis
tuberculous pleural effusion
tuberculous spondylitis; Pott's disease
General
Mycobacterium
Properties
KINGDOM: monera
DIVISION: SCHIZOMYCETES
References
- Cole et al. Nature 393:537-44 1998 (genome sequence)
- Manual of Medical Therapeutics, 28th ed, Ewald &
McKenzie (eds), Little, Brown & Co, Boston, 1995
- Saunders Manual of Medical Practice, Rakel (ed),
WB Saunders, Philadelphia, 1996, pg 183-86
- Journal Watch 20(19):153, 2000
- ARUP Consult: Mycobacterium tuberculosis - TB
The Physician's Guide to Laboratory Test Selection & Interpretation
https://www.arupconsult.com/content/mycobacterium-tuberculosis