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Mycobacterium bovis
Causes HIV-associated mycobacterial infection.
Epidemiology:
- possible airborne transmission (2 cases) [3]
Pathology:
1) cavitary pneumonia
2) disseminated multiorgan disease
Clinical manifestations:
- disseminated multiorgan disease
- chills, recurrent fever, cough, night sweats, diarrhea, muscle weakness, fatigue, anorexia, pleural effusions, hemoptysis, mild splenomegaly (case report [2])
Laboratory:
- see Mycobacterium
Radiology:
- CT of thorax
- diffuse ground-glass opacities throughout both lungs
- pleural effusion (case report [2])
Management:
- isoniazid, rifampin, ethambutol, glucocorticoid [2]
Pharmacology:
- attenuated strain of Mycobacterium bovis used in BCG vaccine [1]
General
Mycobacterium
Properties
KINGDOM: monera
DIVISION: SCHIZOMYCETES
References
- Medical Knowledge Self Assessment Program (MKSAP) 11, 16.
American College of Physicians, Philadelphia 1998, 2012
- Cho JL, McDermott S, Tsibris AM, Mark EJ.
CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL.
Case 37-2015. A 76-Year-Old Man with Fevers, Leukopenia, and
Pulmonary Infiltrates.
N Engl J Med. 2015 Nov 26;373(22):2162-72
PMID: 26605931
http://www.nejm.org/doi/full/10.1056/NEJMcpc1504839
- Buss BF, Keyser-Metobo A, Rother J et al
Possible Airborne Person-to-Person Transmission of
Mycobacterium bovis - Nebraska 2014-2015
MMWR Weekly / March 4, 2016 / 65(8);197-201
http://www.cdc.gov/mmwr/volumes/65/wr/mm6508a1.htm