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MUC-1 vaccine; tecemotide; liposomal BLP25; Stimuvax
Indications:
- in conjunction with standard neoadjuvant systemic therapy improves distant relapse-free survival & overall survival rates in breast cancer patients
Mechanism of action:
- inhibits expression of MUC-1 glycoprotein
- overexpressed in > 90% of breast cancers
- resistant to cancer chemotherapy
General
cancer vaccine
References
- McKnight W
MUC-1 vaccine associated with notable overall survival rates in breast cancer.
MDedge. June 27, 2024
https://ma1.mdedge.com/hematology-oncology/article/269760/breast-cancer/muc-1-vaccine-associated-notable-overall-survival