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mt-tRNA leucine-1 (MT-TL1)

Pathology: - defects in MT-TL1 are associated with - Leigh syndrome - maternally inherited diabetes & deafness - MELAS syndrome - myoclonic epilepsy with ragged-red fibers - progressive external ophthalmoplegia Laboratory: - MT-TL1 gene mutation

General

tRNA leucine-1 (TRNAL1)

Properties

COMPARTMENT: cytoplasm MOTIF: anticodon loop AMINO-ACYL: leucine residue

Database Correlations

OMIM 590050

References

  1. OMIM :accession 590050
  2. Genetics Home Reference MT-TL1: mitochondrially encoded tRNA leucine 1 (UUA/G) https://ghr.nlm.nih.gov/gene/MT-TL1
  3. Wikipedia: MT-TL1 https://en.wikipedia.org/wiki/MT-TL1