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moxetumomab pasudotox (Lumoxiti)

Indications: - treatment of hairy cell leukemia in patients who have failed >=2 previous treatments Adverse effects: boxed warning - risk of hemolytic uremic syndrome & capillary leak syndrome Mechanism of action: - anti-CD22 monoclonal antibody

Interactions

drug adverse effects of pharmaceutical monoclonal antibodies

General

antineoplastic monoclonal antibody

References

  1. Ingram I. Lumoxiti OK'd for Hairy Cell Leukemia - FDA approval marks first anti-CD22 drug for treating the rare disease. MedPage Today. Sept. 13, 2018 https://www.medpagetoday.com/hematologyoncology/leukemia/75087 - FDA News Release. September 13, 2018 FDA approves new kind of treatment for hairy cell leukemia. https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm620448.htm