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monocytosis
Etiology:
1) infection
a) tuberculosis
b) Rocky Mountain spotted fever
c) brucellosis
d) subacute bacterial endocarditis
e) visceral leishmaniasis (kala-azar)
2) malignancies
a) leukemias
b) myeloproliferative syndrome
c) others?
3) hemolytic anemia
4) chronic idiopathic neutropenia
5) granulomatous diseases
- sarcoidosis
6) regional enteritis, inflammatory bowel disease [3]
7) connective tissue diseases
Management:
- persistent monocytosis without obvious infection should be referred for evaluation of possible stem cell disorder, especially when associated with cytopenia(s) [2]
Related
monocyte
General
sign/symptom
References
- Harrison's Principles of Internal Medicine, 13th ed.
Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 334-35
- Medical Knowledge Self Assessment Program (MKSAP) 19
American College of Physicians, Philadelphia 2022
- NEJM Knowledge+ Hematology