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diagnostic error (missed diagnosis)
Etiology:
- most commonly missed diagnoses:
- pneumonia (7%)
- congestive heart failure (6%)
- acute renal failure (5%)
- cancer (5%)
- urinary tract infection (5%)
- poor history-taking, physical exam, or failure to review the medical record account for ~80% of diagnostic errors
- patients with missed diagnoses tend to be older
- medical records associated with diagnostic errors tend to show no documentation of a differential diagnosis at the primary encounter
Management:
- understand diagnostic heuristics [2]
a) availability heuristic
- diagnosis based upon what is most easily available in the physician's mind (i.e. recent or memorable case ..)
b) anchoring (premature closure)
- settling on a diagnosis early in the diagnostic process despite data that refute the diagnosis or support another
c) representativeness
- application of pattern recognition (patient's presentation fits a typical case) thus it must be that case
- utilize diagnostic time outs
- taking time to periodically review a case without assuming the current diagnosis
- plan for worse-case scenario
- consider life-threatening diagnoses 1st
- use systematic approach to common problems
- ask the patient why he/she is sick
- what precipitated the current illness
- utilize clinical examination
- use pretest odds & post-test odds
- acknowledge the effect of the patient
- physicians may discount important data in patients with whom they have had difficult encounter
- physicians close to their patients tend to overestimate prognosis
- look for clinical findings that do not fit the diagnosis
- consider uncommon diagnoses
- slow down & reflect
- difficult to do with many physician's workloads
- admit mistakes [2]
- recognition of limitations may lead to improved quality of care
- working in pairs may reduce diagnostic errors among medical students [3]
- Institute of Medicine Recommendations [4]
- facilitate better teamwork among healthcare workers, patients, & families
- find ways to identify & learn from diagnostic errors (systems approach)
- health IT that supports patients & healthcare workers through the diagnostic process
Notes:
- majority of diagnostic errors involve several contributing factors
- interventions, including policy changes, should be multifaceted [7]
Related
bias
diagnosis
General
medical error
References
- Singh H et al
Types and Origins of Diagnostic Errors in Primary Care Settings.
JAMA Intern Med. 2013;():1-8
PMID: 23440149
http://archinte.jamanetwork.com/article.aspx?articleid=1656540
- Newman-Toker DE and Makary MA
Measuring Diagnostic Errors in Primary Care. Comment on
"Types and Origins of Diagnostic Errors in Primary Care Settings"
JAMA Intern Med. 2013;():1-2
PMID: 23440273
http://archinte.jamanetwork.com/article.aspx?articleid=1656536
- Medical Knowledge Self Assessment Program (MKSAP) 16, 17.
American College of Physicians, Philadelphia 2012, 2015
- Hautz WE et al
Diagnostic Performance by Medical Students Working Individually
or in Teams.
JAMA. 2015;313(3):303-304
PMID: 25603003
http://jama.jamanetwork.com/article.aspx?articleid=2091295
- Institute of Medicine Report. September 22, 2015
Improving Diagnosis in Health Care
http://iom.nationalacademies.org/Reports/2015/Improving-Diagnosis-in-Healthcare.aspx
- Croskerry P.
The importance of cognitive errors in diagnosis and strategies
to minimize them.
Acad Med. 2003 Aug;78(8):775-80. Review.
PMID: 12915363
- Saber Tehrani AS, Lee H, Mathews SC et al
25-Year summary of US malpractice claims for diagnostic errors
1986-2010: an analysis from the National Practitioner Data Bank.
BMJ Qual Saf. 2013 Aug;22(8):672-80.
PMID: 23610443
- Cheraghi-Sohi S, Holland F, Singh H et al
Incidence, origins and avoidable harm of missed opportunities in diagnosis:
longitudinal patient record review in 21 English general practices.
BMJ Qual Saf. 2021;Epub Jun 14.
https://psnet.ahrq.gov/issue/incidence-origins-and-avoidable-harm-missed-opportunities-diagnosis-longitudinal-patient