miR-208

Encoded by an intron of the alpha-MHC gene Function: - upregulates beta-MHC expression in response to stress & hypothyroidism - promotes cardio-myocyte hypertrophy & fibrosis

Properties

GENERAL: short interfering double-stranded RNA; antisense oligonucleotide (siRNA, microRNA, miRNA) FORM: miR-208

References

- van Rooij E et al, Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 2007, 316:575 PMID: 17379774