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mineralocorticoid receptor activation

Pathology: - mineralocorticoid receptor activation by sterois including progesterone Genetics: - mutation in gene for mineralocorticoid receptor Clinical manifestations: - hypertension at young age - exacerbation during pregnancy Laboratory: - plasma renin: low - serum aldosterone: low Management: - thiazide diuretics

Related

mineralocorticoid receptor; MR; nuclear receptor subfamily 3 group C member 2 (NR3C2, MCR, MLR)

General

genetic disease of the endocrine system

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 15, 18. American College of Physicians, Philadelphia 2009, 2018.